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Method comparison between AFIAS-3 POCT and <t>Tosoh</t> <t>G8</t> <t>HPLC</t> for <t>HbA1c.</t> (a) Passing–Bablok regression showing strong correlation (r = 0.98, P < 0.0001; slope = 0.95; intercept = 0.32%). The blue area indicates the 95% confidence interval. (b) Bland–Altman plot showing a negligible mean bias of −0.03% (blue line) with 95% limits of agreement (red lines) ranging from −0.60% to +0.53%. HbA1c: hemoglobin A1c; POCT: point-of-care testing; <t>HPLC:</t> <t>high-performance</t> liquid chromatography.
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Method comparison between AFIAS-3 POCT and <t>Tosoh</t> <t>G8</t> <t>HPLC</t> for <t>HbA1c.</t> (a) Passing–Bablok regression showing strong correlation (r = 0.98, P < 0.0001; slope = 0.95; intercept = 0.32%). The blue area indicates the 95% confidence interval. (b) Bland–Altman plot showing a negligible mean bias of −0.03% (blue line) with 95% limits of agreement (red lines) ranging from −0.60% to +0.53%. HbA1c: hemoglobin A1c; POCT: point-of-care testing; <t>HPLC:</t> <t>high-performance</t> liquid chromatography.
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Method comparison between AFIAS-3 POCT and Tosoh G8 HPLC for HbA1c. (a) Passing–Bablok regression showing strong correlation (r = 0.98, P < 0.0001; slope = 0.95; intercept = 0.32%). The blue area indicates the 95% confidence interval. (b) Bland–Altman plot showing a negligible mean bias of −0.03% (blue line) with 95% limits of agreement (red lines) ranging from −0.60% to +0.53%. HbA1c: hemoglobin A1c; POCT: point-of-care testing; HPLC: high-performance liquid chromatography.

Journal: Cardiology Research

Article Title: Analytical Evaluation of a Point-of-Care Platform for Glycated Hemoglobin and N-Terminal Pro-B-Type Natriuretic Peptide Testing in Cardiometabolic Care

doi: 10.14740/cr2220

Figure Lengend Snippet: Method comparison between AFIAS-3 POCT and Tosoh G8 HPLC for HbA1c. (a) Passing–Bablok regression showing strong correlation (r = 0.98, P < 0.0001; slope = 0.95; intercept = 0.32%). The blue area indicates the 95% confidence interval. (b) Bland–Altman plot showing a negligible mean bias of −0.03% (blue line) with 95% limits of agreement (red lines) ranging from −0.60% to +0.53%. HbA1c: hemoglobin A1c; POCT: point-of-care testing; HPLC: high-performance liquid chromatography.

Article Snippet: Comparators were: 1) HbA1c: Tosoh G8 high-performance liquid chromatography (HPLC) (NGSP-certified, IFCC-traceable); 2) NT-proBNP: cobas 8000 module e602 (Roche Diagnostics), electrochemiluminescence immunoassay (ECLIA).

Techniques: Comparison, High Performance Liquid Chromatography